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Pre-Prints:


Peer-reviewed Journal Papers:

(51) C. Busch, T. Mulholland, M. Zagnoni, et al. "Overcoming BCR::ABL1 dependent and independent survival mechanisms in chronic myeloid leukaemia using a multi-kinase targeting approach", Cell Commun Signal, 2023, 21, 342.

(50)
E. Smith, M. Zagnoni, M.E.Sandison, "Cellular microarrays for assessing single-cell phenotypic changes in vascular cell populations", Biomedical Microdevices, 2023, 25,11.

(49)
H. Bissig, O. Büker, K. Stolt, E. Batista, M. Zagnoni, R. Vroman, H. Kjeldsen, A. Niemann, J. Morgan, J. Schroeter, "Calibration of Insulin pumps based on discrete doses at given cycle times", Biomedical Engineering  / Biomedizinische Technik, 2022, accepted.

(48) K. Paterson, S. Paterson, T. Mulholland, S. Coffelt, M. Zagnoni, "Assessment of CAR-T mediated and targeted cytotoxicity in 3D microfluidic TBNC co-culture models for combination therapy", IEEE OJEMB, 2022, 3, 86-95.

(47) D. Megarity, R. Vroman, M. Kriek, P. Downey, T. J. Bushell, M. Zagnoni, "A modular microfluidic platform to enable complex and customisable in vitro models for neuroscience", Lab Chip, 2022, 22, 1989-2000.

(46)
E. Kay, K. Paterson, et al., M. Zagnoni, S. Zanivan, "PYCR1-dependent proline synthesis in cancer-associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix", Nature Metabolism, 2022, 4 (6), 693-710.

(45)
K. Paterson, S. Zanivan, R. Glasspool, S. B. Coffelt, M. Zagnoni, "Microfluidic technologies for immunotherapy studies in solid tumours", Lab Chip, 2021, 21, 2306 - 2329.

(44) E. L. V. Malavasi, A. Ghosh, D. G. Booth, M. Zagnoni, D. L. Sherman, P. J. Brophy, "Dynamic early clusters of nodal proteins contribute to node of Ranvier assembly during myelination of peripheral neurons", Elife, 2021, 10, e68089.

(43) A. Kapara, K. A. Findlay Paterson, V. G. Brunton, D. Graham, M. Zagnoni, K. Faulds, "Detection of Estrogen Receptor Alpha and Assessment of Fulvestrant Activity in MCF-7 Tumour Spheroids Using Microfluidics and SERS", Anal. Chem., 2021, 93, 14, 5862-5871.

(42) Y. Zhang, Z. Wang, D. New, and M. Zagnoni, "Microdroplet Operations in Polymeric Microtubes", Anal. Chem., 2021, 93, 4, 2411–2418.

(41) P. M. Holloway, S. Willaime-Morawek, R. Siow, M. Barber, R. M. Owens, A. D. Sharma, W. Rowan, E. Hill, M. Zagnoni, "Advances in microfluidic in vitro systems for neurological disease modelling", J Neurosci Res. 2021; 99: 1276– 1307.

(40) L. Tweedy, P. A. Thomason, P. I. Paschke, K. Martin, L. M. Machesky, M. Zagnoni, R. H. Insall, "Seeing around corners: Cells solve mazes and respond at a distance using attractant breakdown", Science, 2020, 369, 6507.

(39)
A. Katsikoudi, E. Ficulle, A. Cavallini, G. Sharman, A. Guyot, M. Zagnoni, B. J. Eastwood, M. Hutton and S. Bose, "Quantitative propagation of assembled human Tau from Alzheimer's disease brain in microfluidic neuronal cultures", Journal of Biological Chemistry, 2020, 295 (37), 13079-13093.

(38)
S. Licht-Mayer, G. R. Campbell, M. Canizares, A. R. Mehta, A. B. Gane, K. McGill, A. Ghosh, A. Fullerton, N. Menezes, J. Dean, J. Dunham, S. Al-Azki, G. Pryce, S. Zandee, C. Zhao, M. Kipp, K. J. Smith, D. Baker, D. Altmann, S. M. Anderton, Y. S. Kap, J. D. Laman, B. A.‘t Hart, M. Rodriguez, R. Watzlawick, J. M. Schwab, R. Carter, N. Morton, M Zagnoni, R. J. M. Franklin, R. Mitchell, S. Fleetwood-Walker, D. A. Lyons, S. Chandran, H. Lassmann, B. D. Trapp & D. J. Mahad, "Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis", Acta Neuropathol 140, 143–167 (2020).

(37)
Y. Zhang, H. Bracken, C. Woolhead, M. Zagnoni, "Functionalisation of human chloride intracellular ion channels in microfluidic droplet-interface-bilayers", Biosens. Bioelectron., 2020, 150, 111920.

(36) T. Mulholland, M. McAllister, S. Patek, D. Flint, M. Underwood, A. Sim, J. Edwards and M. Zagnoni, “Drug screening of biopsy-derived spheroids using a self-generated microfluidic concentration gradient", Sci. Rep., 2018, 8, 14672.

(35)
M. R. Willner, K. S. McMillan, D. Graham, P. J. Vikesland and M. Zagnoni, “Surface-Enhanced Raman Scattering Based Microfluidics for Single-2 Cell Analysis", Anal. Chem., 2018, 90 (20), 12004-12010.

(34)
L. Ritchie, R. Tate, L. H. Chamberlain, G. Robertson, M. Zagnoni, T. Sposito, S. Wray, J. A. Wright, C. E. Bryant, N. J. Gay, T. J. Bushell, “Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons, Neuropharmacol., 2018, 135, 1-10.

(33)
C. MacKerron, G. Robertson, M. Zagnoni & T. J. Bushell, “A Microfluidic Platform for the Characterisation of CNS Active Compounds, Sci. Rep., 2017, 7, 15692.

(32)
A. J. Samson, G. Robertson, M. Zagnoni & C. N. Connolly, “Neuronal networks provide rapid neuroprotection against spreading toxicity”, Sci. Rep., 2016, 6, 33746.

(31) K. S. McMillan, M. Boyd & M. Zagnoni, “Transitioning from multi-phase to single-phase microfluidics for long-term culture and treatment of multicellular spheroids”, Lab Chip, 2016, 16, 3548 - 3557.

(30)
C. A. Cunha-Matos, O. R. Millington, A. W. Wark & M. Zagnoni, “Real-time assessment of nanoparticle-mediated antigen delivery and cell response”, Lab Chip, 2016, 16, 3371-3381.

(29)
K. S. McMillan, A. G. McCluskey, A. Sorensen, M. Boyd & M. Zagnoni, “Emulsion Technologies for Multicellular Tumour Spheroid Radiation Assays”, Analyst, 2016, 141, 100-110.

(28) T. Sposito, E. Preza, C. J. Mahoney, N. Setó-Salvia, N. S. Ryan, H. R. Morris, C. Arber, M. J. Devine, H. Houlden, T. T. Warner, T. J. Bushell, M. Zagnoni, T. Kunath, F. J. Livesey, N. C. Fox, M. N. Rossor, J. Hardy and S. Wray, “Developmental regulation of tau splicing is disrupted in stem cell derived neurons from frontotemporal dementia patients with the 10+16 splice-site mutation in MAPT”, Human Molecular Genetics. 2015, 24 (18), 5260-5269.

(27) B. Schlicht, M. Zagnoni, “Droplet-interface-bilayer assays in microfluidic passive networks”, Sci. Rep. 2015, 5, 9951.

(26) A. Duduś, R. Blue, M. Zagnoni, G. Stewart and D. Uttamchandani, “Modeling and Characterization of an Electrowetting-Based Single-Mode Fiber Variable Optical Attenuator”, JSTQE, 2015, 21, 4, 9, 4500209.

(25) A. McLintock, C. A. Cunha-Matos, M. Zagnoni, O. R. Millington, and A. W. Wark, “Universal Surface-Enhanced Raman Tags: Individual Nanorods for Measurements from the Visible to the Infrared (514 – 1064 nm)”, ACS Nano, 2014, 8, 8600-8609.

(24) A. Duduś, R. Blue, M. Zagnoni, G Stewart and D. Uttamchandani, “In-line single-mode fiber variable optical attenuator based on electrically addressable microdroplets”, Applied Physics Letters, 2014, 105, 021105.

(23) G. Robertson, T.J. Bushell and M. Zagnoni, “Chemically induced synaptic activity between mixed primary hippocampal co-cultures in a microfluidic system”, Integrative Biology, 2014, 6, 636-644.

(22) S. Bai, S. Debnath, K. Gibson, B. Schlicht, L. Bayne, M. Zagnoni and R. V. Ulijn, “Biocatalytic Self-Assembly of Nanostructured Peptide Microparticles using Droplet Microfluidics”, Small, 2014, 10, 285–293.

(21) M. Zagnoni, “Miniaturised technologies for the development of artificial lipid bilayer systems”, Lab Chip, 2012, 12, 1026–1039.

(20) G. J. T. Cooper, P. J. Kitson, R. Winter, M. Zagnoni, D. Long, and L. Cronin, “Modular Redox-Active Inorganic Chemical Cells: iCHELLs”, Angew. Chem. Int. Ed., 2011, 50, 10373-10376.

(19) C. Martino, M. Zagnoni, M. E. Sandison, M. Chanasakulniyom, A. Pitt, J. M. Cooper, “Intracellular Protein Determination using Droplet-Based Immunoassays”, Anal. Chem., 2011, 83, 5361–5368.

(18) A. Rossetti, R. Codeluppi, A. Golfarelli, M. Zagnoni, A. Talamelli and M.Tartagni, “Design and Characterisation of Polymeric Pressure Sensors for Wireless Wind Sail Monitoring”, Sens. Actuat. A., 2011, 167, 162–170.

(17) M. Zagnoni, J. M. Cooper, “A Microdroplet-based Shift Register”, Lab. Chip, 2010, 10, 3069-3073. Highlighted in Chemical & Engineering News, 88 (40), October 04, 2010.

(16) M. Zagnoni, G, Lelaing, J. M. Cooper, “Electrocoalescence Mechanisms of Microdroplets Using Localized Electric Fields in Microfluidic Channels”, Langmuir, 2010, 26, 14443–14449.

(15) M. Zagnoni, J. Anderson; J. M. Cooper, “Hysteresis in Multiphase Microfluidics at a T-Junction”, Langmuir, 2010, 26, 9416-9422.

(14) M. Zagnoni, C. N. Baroud, J. M. Cooper, “Electrically initiated upstream coalescence cascade of droplets in a microfluidic flow”, Phys. Rev. E, 2009, 80, 046303.

(13) D. Wlodkowic, S. Faley, M. Zagnoni, J. P. Wikswo, J. M. Cooper, “Microfluidic Single Cell Array Cytometry for the Analysis of Tumour Apoptosis”, Anal. Chem., 2009, 81, 5517-5523.

(12) M. Zagnoni, J. M. Cooper, “On-chip electrocoalescence of microdroplets as a function of voltage, frequency and droplet size”, Lab Chip, 2009, 9, 2652-2658.

(11) M. Zagnoni, M. E. Sandison, P. Marius, H. Morgan, “Bilayer Lipid Membranes from Falling Droplets”, Anal. Bioanal. Chem., 2009, 393, 1601–1605.

(10) M. Zagnoni, M. E. Sandison, H. Morgan, “Microfluidic array platform for simultaneous lipid bilayer membrane formation”, Biosens. Bioelectron., 2009, 24, 1235–1240.

(9) S. Aghdaei, M. E. Sandison, M. Zagnoni, N. G. Green, H. Morgan, “Formation of artificial lipid bilayers using droplet dielectrophoresis”, Lab Chip, 2008, 8, 1617–1620.

(8) P. Marius, M. Zagnoni, M. E. Sandison, J. M. East, H. Morgan and A. G. Lee, “Binding of Anionic Lipids to at Least Three Non-Annular Sites on the Potassium Channel KcsA is Required for Channel Opening”, Biophys. J., 2008, 94, 1-10.

(7) M. Zagnoni, M. E. Sandison, P. Marius, A. G. Lee and H. Morgan, “Controlled delivery of proteins into bilayer lipid membranes on chip”, Lab Chip, 2007, 7, 1176 -1183.

(6) M. E. Sandison, M. Zagnoni, and H. Morgan, “An Air-Exposure Technique for the Formation of Artificial Lipid Bilayers in Microsystems”, Langmuir, 2007, 23, 8277-8284.

(5) M. E. Sandison, M. Zagnoni, M. Abu-Hantash  and H. Morgan, “Micromachined glass apertures for artificial lipid bilayer formation in a microfluidic system”, J. Micromech. Microeng., 2007, 17, S189-S196.

(4) M. R. R. de Planque, G. P. Mendes, M. Zagnoni, M. E. Sandison, K. H. Fisher, R. M. Berry, A. Watts and H. Morgan, “Controlled delivery of membrane proteins to artificial lipid bilayers by nystatin-ergosterol modulated vesicle fusion”, IEE Proc. Nanobiotechnol., 2006, 153, 21-30.

(3) S. Callegari, M. Zagnoni, A. Golfarelli, M. Tartagni, A. Talamelli, P. Proli, and A. Rossetti, “Experiments on a aircraft flight parameter detection by on-skin sensors”, Sens. Actuat. A, 2006, 130-131, 155-165.

(2) S. Callegari, G. Merendino, A. Golfarelli, M. Zagnoni and M. Tartagni, “Applicability of Field Programmable Analog Arrays to Capacitive Sensing in the Sub-pF Range”, Analog Integrated Circuits and Signal Processing, 2006, 47, N.1, 39-51.

(1) M. Zagnoni, A. Golfarelli, P. Proli, S. Callegari, A. Talamelli, E. Sangiorgi and, M. Tartagni, “A Non Invasive Capacitive Sensor Strip for Aerodynamics Pressure Measurement”, Sens. Actuat. A, 2005, 123-124,  240-248.
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© Copyright 2017-2023 by Michele Zagnoni